TK-685
TK-685 is an orally active, selective, and allosteric SHP2 inhibitor with an IC50 of 2.1 nM. TK-685 inhibits esophageal cancer cell proliferation and induced apoptosis by targeting SHP2-mediated AKT and ERK signaling pathways.
For research use only. We do not sell to patients.
- Formula: C18H20Cl2N6OS
- Molecular Weight:439.36
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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Molecular Weight 439.36
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Formula C18H20Cl2N6OS
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SMILES
ClC1=C(C=CC=C1SC2=NNC(N=C(N3)N4CCC(C)(CC4)CN)=C2C3=O)Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)