ZINC13466751
Based on 1 Customer Validation
ZINC13466751 is a potent inhibitor of HIF-1α/von Hippel-Lindau interaction with an IC50 of 2.0 µM.
For research use only. We do not sell to patients.
- Purity: 99.94%
- CAS No.: 117953-17-0
- Formula: C20H21N5O2
- Molecular Weight:363.41
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Storage:
-20°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
IC50: 2.0 µM (HIF-1α/von Hippel-Lindau)[1]
Chemical Information
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CAS No. 117953-17-0
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Appearance Solid
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Molecular Weight 363.41
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Formula C20H21N5O2
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Color Pink to red
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SMILES
O=C(N(C1=CC=CC=C1)N=C/2C)C2=N/NC3=CC=C(N4CCOCC4)C=C3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Solvent & Solubility
DMSO : 20 mg/mL (55.03 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (268 KB)
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SDS (614 KB)
- English - EN (614 KB)
- Français - FR (614 KB)
- Deutsch - DE (614 KB)
- Norwegian - NO (614 KB)
- Español - ES (614 KB)
- Swedish - SV (614 KB)
- Italian - IT (614 KB)
- Korean - KR (614 KB)
- Portuguese - PT (614 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.7517 mL | 13.7586 mL | 27.5171 mL | 68.7928 mL |
| 5 mM | 0.5503 mL | 2.7517 mL | 5.5034 mL | 13.7586 mL | |
| 10 mM | 0.2752 mL | 1.3759 mL | 2.7517 mL | 6.8793 mL | |
| 15 mM | 0.1834 mL | 0.9172 mL | 1.8345 mL | 4.5862 mL | |
| 20 mM | 0.1376 mL | 0.6879 mL | 1.3759 mL | 3.4396 mL | |
| 25 mM | 0.1101 mL | 0.5503 mL | 1.1007 mL | 2.7517 mL | |
| 30 mM | 0.0917 mL | 0.4586 mL | 0.9172 mL | 2.2931 mL | |
| 40 mM | 0.0688 mL | 0.3440 mL | 0.6879 mL | 1.7198 mL | |
| 50 mM | 0.0550 mL | 0.2752 mL | 0.5503 mL | 1.3759 mL |
ZINC13466751 Related Classifications
HY-101028 Related Classifications
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