DLG-41nc
DLG-41nc is the negative control for DLG-41 (HY-180183). DLG-41nc shows no GAS41 YEATS domain inhibition (IC50: >50 μM in AlphaLISA). DLG-41 has anticancer activity against NSCLC.
For research use only. We do not sell to patients.
- Formula: C31H34N6O3S2
- Molecular Weight:602.77
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
IC50 & Target
IC50: >50 μM (GAS41 YEATS) in AlphaLISA[1]
Chemical Information
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Molecular Weight 602.77
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Formula C31H34N6O3S2
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SMILES
CC1(CN[C@@H](C1)C(NC2=NC=C(S2)C(N3CC(C4=NC=C(C5=C6C(C=CC=C6)=C(C=C5)CNC(CC)=O)S4)C3)=O)=O)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)