Mybl1 - myeloblastosis oncogene-like 1 Gene

Also Known as A-myb; repro9; G1-419-6

Species: Mus musculus

Gene Type: protein coding
Gene ID: 17864

Summary

Enables DNA-binding transcription activator activity, RNA polymerase II-specific. Involved in several processes, including male gamete generation; negative regulation of transposition; and piRNA biosynthetic process. Located in nucleus. Is expressed in several structures, including central nervous system; early conceptus; genitourinary system; hemolymphoid system gland; and sensory organ. Orthologous to human MYBL1 (MYB proto-oncogene like 1). [provided by Alliance of Genome Resources, Apr 2022]

Mybl1 Products (2)

mRNA Protein Name
NM_001290397.1 NP_001277326.1 myb-related protein A isoform 2
NM_008651.3 NP_032677.2 myb-related protein A isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables DNA-binding transcription activator activity, RNA polymerase II-specific IDA
IDA: Inferred from direct assay
29848638 MGI
enables DNA-binding transcription factor activity, RNA polymerase II-specific IDA
IDA: Inferred from direct assay
23523368 MGI
enables promoter-specific chromatin binding IDA
IDA: Inferred from direct assay
26624618 MGI
Biological Process GO Annotation Evidence References Source
involved in male meiosis I IMP
IMP: Inferred from mutant phenotype
21750041 MGI
involved in positive regulation of piRNA transcription IDA
IDA: Inferred from direct assay
23523368 MGI
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
23523368 MGI
involved in positive regulation of transcription by RNA polymerase II IMP
IMP: Inferred from mutant phenotype
21750041 MGI
involved in spermatogenesis IMP
IMP: Inferred from mutant phenotype
21750041 MGI
Cellular Component GO Annotation Evidence References Source
located in nucleus IDA
IDA: Inferred from direct assay
21750041 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

myb-related protein A

  • myb-like protein 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS08871 MYBL1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21658 Mybl1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28176 Mybl1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mybl1 NCBI NCBI:4603