Machilin A
Machilin A is a lignan isolated from the methanolic extract of Phoebe bark. Machilin A inhibits melanin biosynthesis in B-16 mouse melanoma cells with an IC50 of 39.9 μM.
For research use only. We do not sell to patients.
- CAS No.: 110269-50-6
- Formula: C20H22O4
- Molecular Weight:326.39
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| A-375 | IC50 |
235.5 μM
Compound: 2d
|
Cytotoxicity against human A375 cells after 5 days by MTT assay
Cytotoxicity against human A375 cells after 5 days by MTT assay
|
[PMID: 19615898] |
| HepG2 | IC50 |
175.3 μM
Compound: 2d
|
Cytotoxicity against human HepG2 cells after 5 days by MTT assay
Cytotoxicity against human HepG2 cells after 5 days by MTT assay
|
[PMID: 19615898] |
| HT-29 | IC50 |
89.9 μM
Compound: 2d
|
Cytotoxicity against human HT-29 cells after 5 days by MTT assay
Cytotoxicity against human HT-29 cells after 5 days by MTT assay
|
[PMID: 19615898] |
| MCF7 | IC50 |
102.7 μM
Compound: 2d
|
Cytotoxicity against human MCF7 cells after 5 days by MTT assay
Cytotoxicity against human MCF7 cells after 5 days by MTT assay
|
[PMID: 19615898] |
Chemical Information
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CAS No. 110269-50-6
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Molecular Weight 326.39
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Formula C20H22O4
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SMILES
C[C@H](CC1=CC=C(OCO2)C2=C1)[C@@H](C)CC3=CC=C(OCO4)C4=C3
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)