Nutlin-3a (Standard)
Nutlin-3a (Standard) is the analytical standard of Nutlin-3a (HY-10029). This product is intended for research and analytical applications. Nutlin-3a (Rebemadlin), an active enantiomer of Nutlin-3, is a potent murine double minute (MDM2) inhibitor (IC50=90 nM). Nutlin-3a inhibits MDM2-p53 interactions and stabilizes the p53 protein, and induces cell autophagy and apoptosis. Nutlin-3a has the potential for the study of TP53 wild-type ovarian carcinomas.
For research use only. We do not sell to patients.
- Purity : 95%
- CAS No.: 675576-98-4
- Formula: C30H30Cl2N4O4
- Molecular Weight:581.49
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Product Information
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Chemical Information
- Purity & Documentation
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Help & FAQs
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HY-10029
Nutlin-3aMDM2 Antagonist -
HY-19980
Eprenetapoptp53 Activator -
HY-19980A
PRIMA-1Mutant p53 Reactivator -
HY-15676
IdasanutlinMDM2 Inhibitor -
HY-15484
Pifithrin-α hydrobromidep53 Inhibitor -
HY-10959
RG7112MDM2 Antagonist -
HY-12296
NavtemadlinMDM2-p53 Interaction Inhibitor -
HY-101266
MilademetanMDM2 Inhibitor -
HY-18658
Siremadlinp53-MDM2 Inhibitor -
HY-15954
NVP-CGM097MDM2 Inhibitor -
HY-101518
AlrizomadlinMDM2 Inhibitor -
HY-50696
Nutlin-3p53-MDM2 Inhibitor
Product Information
Information
Application
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 675576-98-4
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Molecular Weight 581.49
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Formula C30H30Cl2N4O4
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SMILES
O=C(N1C(C2=C(C=C(C=C2)OC)OC(C)C)=N[C@H]([C@H]1C3=CC=C(C=C3)Cl)C4=CC=C(C=C4)Cl)N5CC(NCC5)=O
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Synonyms
Rebemadlin (Standard)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Nutlin-3a (Standard) Related Classifications
HY-10029R Related Classifications
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