Terrestribisamide
Terrestribisamide ((E)-N,N′-Diferuloylputrescine) can be isolated from dried fruits of Tribulus terrestris. Terrestribisamide has antibacterial, antifungal, antioxidant, anticancer effects.
For research use only. We do not sell to patients.
- CAS No.: 91000-13-4
- Formula: C24H28N2O6
- Molecular Weight:440.49
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| B16-F1 | IC50 |
>150 μM
Compound: 12
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Antimelanogenic activity in mouse B16-F1 cells assessed as reduction in alpha-MSH-stimulated melanin production preincubated for 72 hrs followed by alpha-MSH-stimulation and measured after 2 hrs
Antimelanogenic activity in mouse B16-F1 cells assessed as reduction in alpha-MSH-stimulated melanin production preincubated for 72 hrs followed by alpha-MSH-stimulation and measured after 2 hrs
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[PMID: 30446440] |
| B16-F1 | IC50 |
88.4 μM
Compound: 12
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Inhibition of tyrosinase in mouse B16-F1 cells
Inhibition of tyrosinase in mouse B16-F1 cells
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[PMID: 30446440] |
| COLO 320 | IC50 |
50 μg/mL
Compound: 1
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Cytotoxicity against Homo sapiens (human) COLO320 cells by MTT assay
Cytotoxicity against Homo sapiens (human) COLO320 cells by MTT assay
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10.1007/s00044-012-0393-3 |
Chemical Information
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CAS No. 91000-13-4
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Molecular Weight 440.49
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Formula C24H28N2O6
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SMILES
COC(C=C1/C=C/C(NCCCCNC(/C=C/C2=CC(OC)=C(C=C2)O)=O)=O)=C(C=C1)O
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Synonyms
(E)-N,N′-Diferuloylputrescine
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Research Protocol for Infectious Diseases
Infectious-disease experiments test how pathogens interact with host barriers, innate immune receptors, inflammatory signaling, pathogen replication, and tissue injury; pattern-recognition receptors such as TLRs, RIG-I-like receptors, NOD-like receptors, and inflammasomes detect microbial molecules and activate NF-κB, interferon, and cytokine responses. The central hypothesis is that infection severity reflects the balance between pathogen burden and host response: protective inflammation restricts pathogen growth, whereas excessive or mislocalized inflammation contributes to tissue damage and disease phenotype. Unresolved questions include which host pathways are protective versus pathogenic, why some infection models fail to translate to human disease, and which combined readouts best predict clinically relevant infection outcomes.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Terrestribisamide Related Classifications
HY-N12267A Related Classifications
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