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United States

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製品番号: HY-P12360

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4T1pep1

4T1pep1 is a tumor-homing cyclic peptide obtained through phage display screening. 4T1pep1 binds to mouse 4T1 triple-negative breast cancer cells and human MDA-MB-231 triple-negative breast cancer cells. 4T1pep1 is useful for triple-negative breast cancer-related research.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

分子式: C₃₂H₅₄N₁₀O₁₅S₂
分子量:882.96

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

カスタムペプチド

4T1pep1 構造式

価格（税別）

Amount: USD 0.00

* アイテムを追加する前、数量をご選択ください

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

体外実験

4T1pep1 exhibits high binding affinity and selectivity for 4T1 cells, and it also binds to human MDA-MB-231 cells, while showing no affinity for control 3T3 cells; its potential target is Mucin-16^[1].
4T1pep1 is a novel peptide ligand identified against a mouse triple-negative breast cancer cell line through in vitro phage display biopanning, and it holds potential for nano-targeted delivery in TNBC therapy^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.

化学情報

分子量 882.96
分子式 C₃₂H₅₄N₁₀O₁₅S₂
配列

Cys-Pro-Thr-Ala-Ser-Asn-Thr-Ser-Cys
シーケンスの短縮

CPTASNTSC
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

プロトコル

All Animals and Diseases

Breast Cancer Modeling
Breast cancer is a heterogeneous cancer, and it has been distinguished into four subtypes: luminal A, luminal B, HER2-positive and basal-like. Molecular mutations, epigenetic alterations, hormone exposure and immune microenvironment are related to the progression of breast cancer.

純度とドキュメンテーション

取扱説明書 (2659 KB)

参考文献

[1]. Silva V L, et al. Selection of Novel Peptides Homing the 4T1 CELL Line: Exploring Alternative Targets for Triple Negative Breast Cancer. PLOS ONE, 2016, 11(8): e0161290.

[2]. Abbaszadeh F. Bacteriophages: cancer diagnosis, treatment, and future prospects. Journal of Pharmaceutical Investigation. 2021 Jan;51(1):23-34.

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

濃度濃度

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分子量分子量

希釈計算機

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濃度 _(開始) 濃度 _(開始)

体積 _(開始) 体積 _(開始)

濃度 _(終了) 濃度 _(終了)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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