AA-CW236
Based on 1 Customer Validation
AA-CW236 is a MGMT (O6-methylguanine DNA methyltransferase) inhibitor. AA-CW236 targets MGMT active site Cys145 for covalent modification.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.9%
- CAS 番号: 1869921-96-9
- 分子式: C17H16ClF3N4O2
- 分子量:400.78
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
DNA Methyltransferase アイソフォーム固有の製品をすべて表示
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生物活性
化学情報
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CAS 番号 1869921-96-9
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性状 Solid
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分子量 400.78
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分子式 C17H16ClF3N4O2
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Color White to off-white
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SMILES
FC(F)(F)OC1=CC=C(C2=C(CCl)N(CCC3=C(C)ON=C3C)N=N2)C=C1
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
DMSO : 25 mg/mL (62.38 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (268 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.4951 mL | 12.4757 mL | 24.9513 mL | 62.3784 mL |
| 5 mM | 0.4990 mL | 2.4951 mL | 4.9903 mL | 12.4757 mL | |
| 10 mM | 0.2495 mL | 1.2476 mL | 2.4951 mL | 6.2378 mL | |
| 15 mM | 0.1663 mL | 0.8317 mL | 1.6634 mL | 4.1586 mL | |
| 20 mM | 0.1248 mL | 0.6238 mL | 1.2476 mL | 3.1189 mL | |
| 25 mM | 0.0998 mL | 0.4990 mL | 0.9981 mL | 2.4951 mL | |
| 30 mM | 0.0832 mL | 0.4159 mL | 0.8317 mL | 2.0793 mL | |
| 40 mM | 0.0624 mL | 0.3119 mL | 0.6238 mL | 1.5595 mL | |
| 50 mM | 0.0499 mL | 0.2495 mL | 0.4990 mL | 1.2476 mL | |
| 60 mM | 0.0416 mL | 0.2079 mL | 0.4159 mL | 1.0396 mL |