ABD56
ABD56 is a compound that induces osteoclast apoptosis and has the activity of inhibiting osteoclast formation and inducing apoptosis. ABD56 can inhibit osteoclast formation and induce apoptosis, and its mechanism is related to the inhibition of NFκB and ERK pathways.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 521294-19-9
- 分子式: C17H18O3
- 分子量:270.32
-
保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
製品説明
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| Hepatocyte | IC50 |
>200 μM
Compound: 67, ABD56
|
Effect on apoptosis of hepatocyte
Effect on apoptosis of hepatocyte
|
[PMID: 17149877] |
| Osteoblast | IC50 |
>100 μM
Compound: 67, ABD56
|
Effect on apoptosis of osteoblast
Effect on apoptosis of osteoblast
|
[PMID: 17149877] |
| Osteoclast | IC50 |
9 μM
Compound: 67, ABD56
|
Inhibition of mouse osteoclast survival
Inhibition of mouse osteoclast survival
|
[PMID: 17149877] |
化学情報
-
CAS 番号 521294-19-9
-
分子量 270.32
-
分子式 C17H18O3
-
SMILES
O=C(OCCCCO)C1=CC=C(C=C1)C2=CC=CC=C2
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)