AChE-IN-112
AChE-IN-112 is an acetylcholinesterase (AChE) inhibitor with an IC50 of 0.41 μM. AChE-IN-112 scavenges various reactive oxygen and reactive nitrogen species, including DPPH, ABTS, NO, hydroxyl and hydrogen peroxide free radicals. AChE-IN-112 can be used for the research of Alzheimer's disease.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 分子式: C27H28N4O7S
- 分子量:552.60
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
製品説明
IC50 & Target
[1]|
AChE 0.41 μM (IC50) |
体外実験
AChE-IN-112 (Compound 4r) (62.5 µg/mL) shows weak inhibition of BChE, with 32.51% inhibition at a concentration of 62.5 µg/mL[1].
AChE-IN-112 (10 μg/mL) possesses notable in vitro antioxidant activity, with a total antioxidant capacity of 66.80 mg gallic acid/g, an IRP level of 96.7 µM, and potent radical scavenging activity against DPPH, ABTS, NO, OH, and H2O2 radicals[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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分子量 552.60
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分子式 C27H28N4O7S
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SMILES
CCCS(=O)(OC1=CC(/C=N/NC(COC2=CC=C(C3=NC4=CC=CC=C4N3)C=C2OC)=O)=CC=C1OC)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)