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AChE-IN-6

AChE-IN-6 (Compound 12a) is an optimal multifunctional ligand with significant inhibition of AChE (EeAChE, IC50 = 0.20 μM; HuAChE, IC50 = 37.02 nM) and anti-Aβ activity (IC50 = 1.92 μM for self-induced Aβ1-42 aggregation; IC50 = 1.80 μM for disaggregation of Aβ1-42 fibrils; IC50 = 2.18 μM for Cu2+-induced Aβ1-42 aggregation; IC50 = 1.17 μM for disaggregation of Cu2+-induced Aβ1-42 fibrils). AChE-IN-6 has the potential for the research of Alzheimer's disease.

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  • CAS 番号: 2758788-95-1
  • 分子式: C29H41N5O2
  • 分子量:491.67
  • 保管条件:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • AChE-IN-6 Chemical Structure
    AChE-IN-6 構造式
CAS 番号: 2758788-95-1
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    AChE-IN-6 Chemical Structure
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  • AChE-IN-6