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製品番号: HY-N18106

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Amygdalinic acid

Amygdalinic acid (Compound 3) is a glycoside. Amygdalinic acid can be isolated from Persicae Semen. Amygdalinic acid inhibits Epstein-Barr virus early antigen activation. Amygdalinic acid delays two-stage chemical carcinogenesis in mouse skin, reduces papilloma incidence.

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CAS 番号: 66427-92-7
分子式: C₂₀H₂₈O₁₃
分子量:476.43

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (277 KB)

Amygdalinic acid 構造式

CAS 番号: 66427-92-7

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

体外実験

Amygdalinic acid (10-1000 mol ratio/TPA; 48 h) inhibits EBV-EA activation in Raji cells in a concentration-dependent manner, with the strongest inhibition (3.5 ± 0.3% relative control) observed at 1000 mol ratio/TPA and 60% cell viability^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Immunofluorescence^[1]

Cell Line:

Raji cells (Burkitt's lymphoma-derived lymphoblastoid cells)
Concentration:

10-1000 mol ratio/TPA
Incubation Time:

48 h
Result:

Reduced EBV-EA activation to 3.5 ± 0.3% relative to the positive control, with 60% Raji cell viability at 1000 mol ratio/TPA.
Reduced EBV-EA activation to 34.1 ± 1.2% relative to the positive control, with >80% Raji cell viability at 500 mol ratio/TPA.
Reduced EBV-EA activation to 65.0 ± 1.9% relative to the positive control, with >80% Raji cell viability at 100 mol ratio/TPA.
Reduced EBV-EA activation to 95.7 ± 0.4% relative to the positive control, with >80% Raji cell viability at 10 mol ratio/TPA.

体内実験

Amygdalinic acid (85 nmol; twice weekly) exhibits anti-tumor promoting activity in a two-stage skin carcinogenesis mouse model, reducing the incidence of papillomas to a level comparable to that of (-)-Epigallocatechin gallate (HY-13653)^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

化学情報

CAS 番号 66427-92-7
分子量 476.43
分子式 C₂₀H₂₈O₁₃
SMILES

OC([C@@H](C1=CC=CC=C1)O[C@@H]2O[C@@H]([C@H]([C@@H]([C@H]2O)O)O)CO[C@@H]3O[C@@H]([C@H]([C@@H]([C@H]3O)O)O)CO)=O
Structure Classification
- Ketones, Aldehydes, Acids
Initial Source
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

バッチを選択:

純度: 99.98%

Assay: 99.98%

ee.: 99.98%

データシート (277 KB)
COA (2659 KB)
元素分析報告書 (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
取扱説明書 (2659 KB)

参考文献

[1]. Fukuda T, et al. Anti-tumor promoting effect of glycosides from Prunus persica seeds. Biol Pharm Bull. 2003;26(2):271-273. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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