BJH-60
BJH-60 is a mitochondrial complex 1 inhibitor. BJH-60 can inhibit mitochondrial oxygen consumption rate with an IC50 of 1.9 μM in A549 cells. BJH-60 shows no PDE inhibitory effect. BJH-60 can be used for the research of cancer, such as breast cancer.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 3067849-06-0
- 分子式: C24H21NO2
- 分子量:355.43
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
BJH-60 (3-100 μM, 96 h) inhibits cell proliferation in A549 and EO771 cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:A549 and EO771 cells
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Concentration:3, 10 and 100 μM
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Incubation Time:96 h
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Result:Significantly reduced cell numbers at 100 μM.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:C57Bl6 bearing EO771 mammary gland tumors[1]
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Dosage:2 mg/kg
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Administration:IV; 1 hour before XRT
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Result:Doubled the tumor growth delay to 4 days.
化学情報
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CAS 番号 3067849-06-0
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分子量 355.43
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分子式 C24H21NO2
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SMILES
OCC1=CC=C(C2=CC=CC(CC3=CC=NC4=CC=C(OC)C=C34)=C2)C=C1
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
BJH-60 関連分類
HY-178986 関連分類
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