CB-25
Based on 1 Customer Validation
CB-25 is a ligand of CB1 cannabinoid receptors, acting as a partial agonist. CB-25 enhances Forskolin (HY-15371)-induced cAMP formation in cancer cells but not hCB1-CHO cells.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 98.84%
- CAS 番号: 869376-63-6
- 分子式: C25H41NO3
- 分子量:403.60
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保管条件:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
生物活性
製品説明
Cellular Effect
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| RBL-2H3 | IC50 |
17 μM
Compound: 25
|
Inhibition of anandamide membrane transporter in RBL-2H3 cells assessed as [14C]anandamide uptake
Inhibition of anandamide membrane transporter in RBL-2H3 cells assessed as [14C]anandamide uptake
|
[PMID: 16279794] |
化学情報
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CAS 番号 869376-63-6
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性状 Solid
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分子量 403.60
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分子式 C25H41NO3
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Color White to off-white
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SMILES
O=C(NC1CC1)CCCCCCCCCCOC2=CC(CCCCC)=CC(O)=C2
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
溶剤 & 溶解度
体外:
DMSO : ≥ 100 mg/mL (247.77 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (263 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.4777 mL | 12.3885 mL | 24.7770 mL | 61.9425 mL |
| 5 mM | 0.4955 mL | 2.4777 mL | 4.9554 mL | 12.3885 mL | |
| 10 mM | 0.2478 mL | 1.2389 mL | 2.4777 mL | 6.1943 mL | |
| 15 mM | 0.1652 mL | 0.8259 mL | 1.6518 mL | 4.1295 mL | |
| 20 mM | 0.1239 mL | 0.6194 mL | 1.2389 mL | 3.0971 mL | |
| 25 mM | 0.0991 mL | 0.4955 mL | 0.9911 mL | 2.4777 mL | |
| 30 mM | 0.0826 mL | 0.4130 mL | 0.8259 mL | 2.0648 mL | |
| 40 mM | 0.0619 mL | 0.3097 mL | 0.6194 mL | 1.5486 mL | |
| 50 mM | 0.0496 mL | 0.2478 mL | 0.4955 mL | 1.2389 mL | |
| 60 mM | 0.0413 mL | 0.2065 mL | 0.4130 mL | 1.0324 mL | |
| 80 mM | 0.0310 mL | 0.1549 mL | 0.3097 mL | 0.7743 mL | |
| 100 mM | 0.0248 mL | 0.1239 mL | 0.2478 mL | 0.6194 mL |