Complex I-IN-1
Complex I-IN-1 is a novel fungicide that acts as a mitochondrial complex I inhibitor. Complex I-IN-1 regulates oxidoreductase activity, glycolysis/gluconeogenesis, methionine metabolism, and the MAPK signaling pathway in Blumeria graminis. Complex I-IN-1 is applicable to research related to wheat powdery mildew.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 3080323-62-9
- 分子式: C16H12Cl5F2N3O2
- 分子量:493.55
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
Complex I-IN-1 (compound 3) binds to the active site of yeast mitochondrial Complex I and interacts with surrounding key amino acid residues, which is consistent with its function as a Complex I inhibitor[1].
Complex I-IN-1 exhibits excellent activity against wheat powdery mildew (EC50 = 0.440 mg/L)[1].
Complex I-IN-1 alters gene expression in mycelia of Blumeria graminis, and the differentially expressed genes (DEGs) are enriched in pathways associated with mitochondrial complex I function, confirming complex I as its potential target[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 3080323-62-9
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分子量 493.55
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分子式 C16H12Cl5F2N3O2
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SMILES
Cl/C(Cl)=C/COC1=CC(Cl)=C(OCCNC2=C(Cl)C(C(F)F)=NC=N2)C(Cl)=C1
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Complex I-IN-1 関連分類
HY-184440 関連分類
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