D-Asparagine
Based on 1 Customer Validation
D-Asparagine (H-D-Asn-OH) acts as a competitive inhibitor of L-asparagine hydrolysis, with a Ki value of 0.24 mM. D-Asparagine serves as a nitrogen source for yeast strains. D-Asparagine is a good substrate for external yeast asparaginase but a poor substrate for internal yeast asparaginase.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 98.0%
- CAS 番号: 2058-58-4
- 分子式: C4H8N2O3
- 分子量:132.12
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
Endogenous Metabolite アイソフォーム固有の製品をすべて表示
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生物活性
製品説明
体外実験
D-Asparagine (2-10 mM; 48 h, generation time measured at 21°C) can serve as the sole nitrogen source for growth in extracellular asparaginase-secreting Saccharomyces cerevisiae strains (D273-10B, X2180-A2) and their gap-1 mutants[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 2058-58-4
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性状 Solid
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分子量 132.12
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分子式 C4H8N2O3
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Color White to off-white
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SMILES
N[C@H](CC(N)=O)C(O)=O
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別名
H-D-Asn-OH; D-アスパラギン
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Structure Classification
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Initial Source
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
体外:
H2O : 33.33 mg/mL (252.27 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (270 KB)
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SDS (396 KB)
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- Deutsch - DE (396 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. Dunlop PC, et al. Utilization of D-asparagine by Saccharomyces cerevisiae. J Bacteriol. 1976;125(3):999-1004. [Content Brief]
[2]. Taniguchi A, et al. D-Asparagine is an Ideal Endogenous Molecule for Measuring the Glomerular Filtration Rate. Kidney Int Rep. 2023;8(6):1192-1200. Published 2023 Mar 21. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 7.5689 mL | 37.8444 mL | 75.6888 mL | 189.2219 mL |
| 5 mM | 1.5138 mL | 7.5689 mL | 15.1378 mL | 37.8444 mL | |
| 10 mM | 0.7569 mL | 3.7844 mL | 7.5689 mL | 18.9222 mL | |
| 15 mM | 0.5046 mL | 2.5230 mL | 5.0459 mL | 12.6148 mL | |
| 20 mM | 0.3784 mL | 1.8922 mL | 3.7844 mL | 9.4611 mL | |
| 25 mM | 0.3028 mL | 1.5138 mL | 3.0276 mL | 7.5689 mL | |
| 30 mM | 0.2523 mL | 1.2615 mL | 2.5230 mL | 6.3074 mL | |
| 40 mM | 0.1892 mL | 0.9461 mL | 1.8922 mL | 4.7305 mL | |
| 50 mM | 0.1514 mL | 0.7569 mL | 1.5138 mL | 3.7844 mL | |
| 60 mM | 0.1261 mL | 0.6307 mL | 1.2615 mL | 3.1537 mL | |
| 80 mM | 0.0946 mL | 0.4731 mL | 0.9461 mL | 2.3653 mL | |
| 100 mM | 0.0757 mL | 0.3784 mL | 0.7569 mL | 1.8922 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
D-Asparagine 関連分類
HY-W010378 関連分類
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