(E)-2'-Hydroxy-3,4-dimethoxychalcone
(E)-2'-Hydroxy-3,4-dimethoxychalcone (compound 7) is a Chalcone derivative with orally active. (E)-2'-Hydroxy-3,4-dimethoxychalcone has anti-tumour activities.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 79140-20-8
- 分子式: C17H16O4
- 分子量:284.31
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| MCF7 | IC50 |
95 μM
Compound: 24
|
Growth inhibition of MCF7 cells by sulforhodamine assay
Growth inhibition of MCF7 cells by sulforhodamine assay
|
[PMID: 17383189] |
| MDCK-II | IC50 |
4.97 μM
Compound: 5
|
Inhibition of human BCRP expressed in MDCK2 cells assessed as Hoechst 33342 accumulation preincubated for 30 mins by fluorimetry
Inhibition of human BCRP expressed in MDCK2 cells assessed as Hoechst 33342 accumulation preincubated for 30 mins by fluorimetry
|
[PMID: 22112540] |
| Neutrophil | IC50 |
15 μM
Compound: 13
|
Inhibition of PMA-induce ROS/RNS generation in human neutrophils measured up to 30 mins in presence of 30 mM glucose by luminol-amplified chemiluminescence method
Inhibition of PMA-induce ROS/RNS generation in human neutrophils measured up to 30 mins in presence of 30 mM glucose by luminol-amplified chemiluminescence method
|
[PMID: 33006891] |
| Neutrophil | IC50 |
6.4 μM
Compound: 13
|
Inhibition of PMA-induce ROS/RNS generation in human neutrophils measured up to 30 mins in presence of 5.5 mM glucose by luminol-amplified chemiluminescence method
Inhibition of PMA-induce ROS/RNS generation in human neutrophils measured up to 30 mins in presence of 5.5 mM glucose by luminol-amplified chemiluminescence method
|
[PMID: 33006891] |
| TK-10 | IC50 |
90 μM
Compound: 24
|
Growth inhibition of TK10 cells by sulforhodamine assay
Growth inhibition of TK10 cells by sulforhodamine assay
|
[PMID: 17383189] |
化学情報
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CAS 番号 79140-20-8
-
分子量 284.31
-
分子式 C17H16O4
-
SMILES
O=C(C1=CC=CC=C1O)/C=C/C2=CC=C(OC)C(OC)=C2
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輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)