Echinulin
Based on 1 Customer Validation
Echinulin (Echinuline) is a cyclic dipeptide carrying a triprenylated indole moiety. Echinulin contributes to the activation of T cell subsets, which leads to NF-κB activation.Echinulin exerts its immune roles by the NF-κB pathway.Echinulin has the potential to serve as a immunotherapeutic agent.
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- 純度: 98.63%
- CAS 番号: 1859-87-6
- 分子式: C29H39N3O2
- 分子量:461.64
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保管条件:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
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NF-κB |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| B16-4A5 | IC50 |
68 μM
Compound: 2
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Inhibition of melanogenesis in theophylline-stimulated mouse B16-4A5 cells assessed as reduction in melanin level incubated for 72 hrs
Inhibition of melanogenesis in theophylline-stimulated mouse B16-4A5 cells assessed as reduction in melanin level incubated for 72 hrs
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[PMID: 27641468] |
| BV-2 | IC50 |
>50 μM
Compound: 26
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Inhibition of iNOS-mediated NO production in LPS-induced mouse BV2 cells
Inhibition of iNOS-mediated NO production in LPS-induced mouse BV2 cells
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[PMID: 18926710] |
| MDCK | CC50 |
>200 μM
Compound: 22
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Cytotoxicity against MDCK cells assessed as cell growth after 40 hrs by CellTiter-Glo assay
Cytotoxicity against MDCK cells assessed as cell growth after 40 hrs by CellTiter-Glo assay
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[PMID: 25681711] |
化学情報
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CAS 番号 1859-87-6
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性状 Solid
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分子量 461.64
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分子式 C29H39N3O2
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Color White to off-white
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SMILES
C/C(C)=C\CC1=C2C(C(C[C@H]3C(N[C@H](C(N3)=O)C)=O)=C(C(C)(C)C=C)N2)=CC(C/C=C(C)\C)=C1
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別名
Echinuline
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Structure Classification
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Initial Source
Aspergillus chevalieri
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
純度とドキュメンテーション
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データシート (270 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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取扱説明書 (2659 KB)
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Echinulin 関連分類
HY-N3796 関連分類
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