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製品番号: HY-126955

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Ethylmalonyl-CoA

Name: Ethylmalonyl-CoA
Brand: MedChemExpress
SKU: HY-126955
Availability: PreOrder

(別名: Ethylmalonyl coenzyme A)

Ethylmalonyl-CoA (Ethylmalonyl coenzyme A) is a metabolic intermediate and biosynthetic precursor associated with crotonyl-CoA carboxylase/reductase. Ethylmalonyl‑CoA is generated via the reductive carboxylation of crotonyl-CoA catalyzed by crotonyl-CoA carboxylase/reductase (CCR); it can be recognized by the PKS acyltransferase AT and participate in the biosynthesis of antibiotic polyketide natural products. Ethylmalonyl-CoA is used in biosynthesis-related research.

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CAS 番号: 6049-57-6
分子式: C₂₆H₄₂N₇O₁₉P₃S
分子量:881.63

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (274 KB)

Ethylmalonyl-CoA 構造式

CAS 番号: 6049-57-6

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

Endogenous Metabolite アイソフォーム固有の製品をすべて表示 :

体外実験

Ethylmalonyl‑CoA can be produced via the reductive carboxylation of acetyl-CoA-derived intermediates in cell extracts of Rhodobacter sphaeroides cultured with acetate as the aerobic substrate; it can also be catalyzed to undergo reverse decomposition by purified recombinant Rhodobacter sphaeroides crotonyl-CoA carboxylase/reductase^[1]^[2].
Ethylmalonyl‑CoA serves as a key precursor for the biosynthesis of polyketide natural products including monensin A, sanglifehrin A, davilactone, and bacillomycin ^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .

化学情報

CAS 番号 6049-57-6
分子量 881.63
分子式 C₂₆H₄₂N₇O₁₉P₃S
SMILES

OC(C(CC)C(SCCNC(CCNC([C@H](O)C(C)(C)COP(OP(O)(OC[C@H]1O[C@@H](N(C=N2)C3=C2C(N)=NC=N3)[C@H](O)[C@@H]1OP(O)(O)=O)=O)(O)=O)=O)=O)=O)=O
別名

Ethylmalonyl coenzyme A
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

バッチを選択:

純度: 99.98%

Assay: 99.98%

ee.: 99.98%

データシート (274 KB)
COA (2659 KB)
元素分析報告書 (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
取扱説明書 (2659 KB)

参考文献

[1]. Erb TJ, et al. Synthesis of C5-dicarboxylic acids from C2-units involving crotonyl-CoA carboxylase/reductase: the ethylmalonyl-CoA pathway. Proceedings of the National Academy of Sciences of the United States of America. 2007 Jun 19;104(25):10631-6.

[2]. Wilson MC, et al. Beyond ethylmalonyl-CoA: the functional role of crotonyl-CoA carboxylase/reductase homologs in expanding polyketide diversity. Natural product reports. 2012 Jan;29(1):72-86.

Calculators

モル濃度計算機

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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