Fluorescein-DBCO
Based on 1 Customer Validation
Fluorescein-DBCO is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fluorescein-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 98.02%
- CAS 番号: 2054339-00-1
- 分子式: C39H27N3O6S
- 分子量:665.71
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保管条件:
4°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
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Non-cleavable Linker |
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 2054339-00-1
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性状 Solid
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分子量 665.71
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分子式 C39H27N3O6S
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Color Yellow to orange
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SMILES
O=C(N1CC2=C(C#CC3=C1C=CC=C3)C=CC=C2)CCNC(NC4=CC=C(C5=C4)C6(OC5=O)C7=C(OC8=C6C=CC(O)=C8)C=C(O)C=C7)=S
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
4°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
溶剤 & 溶解度
DMSO : 100 mg/mL (150.22 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (273 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.5022 mL | 7.5108 mL | 15.0216 mL | 37.5539 mL |
| 5 mM | 0.3004 mL | 1.5022 mL | 3.0043 mL | 7.5108 mL | |
| 10 mM | 0.1502 mL | 0.7511 mL | 1.5022 mL | 3.7554 mL | |
| 15 mM | 0.1001 mL | 0.5007 mL | 1.0014 mL | 2.5036 mL | |
| 20 mM | 0.0751 mL | 0.3755 mL | 0.7511 mL | 1.8777 mL | |
| 25 mM | 0.0601 mL | 0.3004 mL | 0.6009 mL | 1.5022 mL | |
| 30 mM | 0.0501 mL | 0.2504 mL | 0.5007 mL | 1.2518 mL | |
| 40 mM | 0.0376 mL | 0.1878 mL | 0.3755 mL | 0.9388 mL | |
| 50 mM | 0.0300 mL | 0.1502 mL | 0.3004 mL | 0.7511 mL | |
| 60 mM | 0.0250 mL | 0.1252 mL | 0.2504 mL | 0.6259 mL | |
| 80 mM | 0.0188 mL | 0.0939 mL | 0.1878 mL | 0.4694 mL | |
| 100 mM | 0.0150 mL | 0.0751 mL | 0.1502 mL | 0.3755 mL |
Fluorescein-DBCO 関連分類
HY-126851 関連分類
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