GE 2270A
GE 2270A (MDL 62879) is an antibiotic. GE 2270A inhibits gram-positive bacteria and anaerobes by inhibiting protein synthesis. GE 2270A can be used for the research of infection.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 134861-34-0
- 分子式: C56H55N15O10S6
- 分子量:1290.52
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
Antibiotic アイソフォーム固有の製品をすべて表示
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生物活性
IC50: 0.4 μM (poly(U)-directed poly(Phe) synthesis)[2]
GE 2270A (0.01-100 mg/L) inhibits poly(U)-directed poly(Phe) synthesis in cell-free systems with an IC50 value of 0.12 mg/L[1]. GE 2270A (0-0.1 mM; 10 min) is a strong inhibitor of protein biosynthesis in vitro as determined in a minimal E. coli purified system for poly(U)-directed poly(Phe) synthesis with an IC50 value of 0.4 μM[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 134861-34-0
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分子量 1290.52
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分子式 C56H55N15O10S6
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別名
MDL 62879
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. Landini P, B et al. Inhibition of bacterial protein synthesis by elongation-factor-Tu-binding antibiotics MDL 62,879 and efrotomycin. Biochem J. 1992 May 1;283 ( Pt 3)(Pt 3):649-52. [Content Brief]
[2]. Anborgh PH, Parmeggiani A. New antibiotic that acts specifically on the GTP-bound form of elongation factor Tu. EMBO J. 1991 Apr;10(4):779-84. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
GE 2270A 関連分類
HY-106882 関連分類
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