Chm - choroidermia (RAB escort protein 1) Gene

Also Known as Rep-1

生物種: Mus musculus

遺伝子タイプ: protein coding
遺伝子ID: 12662

Summary

Predicted to enable small GTPase binding activity. Acts upstream of or within blood vessel development. Predicted to be part of Rab-protein geranylgeranyltransferase complex. Predicted to be active in cytosol and nucleus. Is expressed in urethra. Used to study choroideremia. Human ortholog(s) of this gene implicated in choroideremia. Orthologous to human CHM (CHM Rab escort protein). [provided by Alliance of Genome Resources, Apr 2022]

Chm Products (12)

mRNA Protein Name
NM_001370788.1 NP_001357717.1 rab proteins geranylgeranyltransferase component A 1 isoform 2
NM_001370789.1 NP_001357718.1 rab proteins geranylgeranyltransferase component A 1 isoform 3
NM_001370790.1 NP_001357719.1 rab proteins geranylgeranyltransferase component A 1 isoform 4
NM_001409667.1 NP_001396596.1 rab proteins geranylgeranyltransferase component A 1 isoform 5
NM_001409668.1 NP_001396597.1 rab proteins geranylgeranyltransferase component A 1 isoform 6
NM_001409669.1 NP_001396598.1 rab proteins geranylgeranyltransferase component A 1 isoform 7
NM_001409670.1 NP_001396599.1 rab proteins geranylgeranyltransferase component A 1 isoform 8
NM_001409675.1 NP_001396604.1 rab proteins geranylgeranyltransferase component A 1 isoform 8
NM_001409676.1 NP_001396605.1 rab proteins geranylgeranyltransferase component A 1 isoform 8
NM_001409677.1 NP_001396606.1 rab proteins geranylgeranyltransferase component A 1 isoform 9
NM_001409678.1 NP_001396607.1 rab proteins geranylgeranyltransferase component A 1 isoform 7
NM_018818.2 NP_061288.2 rab proteins geranylgeranyltransferase component A 1 isoform 1

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence 参考文献 由来
acts upstream of or within blood vessel development IMP
IMP: Inferred from mutant phenotype
15242790 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

rab proteins geranylgeranyltransferase component A 1

  • choroideraemia protein homolog

  • choroideremia protein homolog

  • rab escort protein 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (8)
製品番号 製品名
製品効果
純度
Rare Diseases
HY-103257 CHM-1 Inhibitor 99.57% Unkown
HY-120482 CHM-1-P-Na Control / Unkown
HY-RS02636 CHM Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS08633 MPZ Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-170700 CHM-FUBIATA / Unkown
HY-RS19561 Chm Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26057 Chm Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W754600 BZO-CHMOXIZID Activator / Unkown

Orthologs Information

生物種 Symbol 由来 ID
Homo sapiens Chm NCBI NCBI:1121