Madcam1 - mucosal vascular addressin cell adhesion molecule 1 Gene

生物種: Rattus norvegicus

遺伝子タイプ: protein coding
遺伝子ID: 54266

Summary

Predicted to enable Integrin binding activity involved in cell-matrix adhesion. Involved in aging; cell adhesion; and positive regulation of leukocyte migration. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. Used to study Crohn's Disease and food Allergy. Orthologous to human MADCAM1 (mucosal vascular addressin cell adhesion molecule 1). [provided by Alliance of Genome Resources, Apr 2022]

Madcam1 Products (1)

mRNA Protein Name
NM_019317.1 NP_062190.1 mucosal addressin cell adhesion molecule 1 precursor

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence 参考文献 由来
involved in cell adhesion IDA
IDA: Inferred from direct assay
12859728 RGD
involved in positive regulation of leukocyte migration IMP
IMP: Inferred from mutant phenotype
14670821 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

mucosal addressin cell adhesion molecule 1

  • MAdCAM-1

  • rMAdCAM-1

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

阻害性抗体 (1)
製品番号 製品名 製品効果
純度 Phase
HY-P99411 Ontamalimab 99.86% Phase 3

Pre-clinical Phase

Bioactive Molecules (6)
製品番号 製品名
製品効果
純度
Rare Diseases
HY-159179 α4 integrin receptor antagonist 3 Inhibitor / Unkown
HY-171216 GW559090 Antagonist / Unkown
HY-177961 α4β7 Integrin-IN-1 Inhibitor / Unkown
HY-RS07952 MADCAM1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19091 Madcam1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25581 Madcam1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
阻害性抗体 (3)
製品番号 製品名
製品効果
純度
Rare Diseases
HY-P990203 Anti-Mouse LPAM-1/Integrin α4β7 Antibody (DATK32) Inhibitor 99.08% Unkown
HY-P991807 Anti-Mouse MAdCAM-1 Antibody (MECA-89) Inhibitor / Unkown
HY-P990197 Anti-Mouse MAdCAM-1 Antibody (MECA-367) Inhibitor 96.72% Unkown

Orthologs Information

生物種 Symbol 由来 ID
Homo sapiens Madcam1 NCBI NCBI:8174