Gluconapin
Gluconapin (3-Butenyl glucosinolate) is an orally active aliphatic glucosinolate and also a flavor modifier. Gluconapin inhibits the elevation of plasma triglyceride levels in mice. Gluconapin also exhibits certain antibacterial activity.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 19041-09-9
- 分子式: C11H19NO9S2
- 分子量:373.40
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
製品説明
体外実験
Gluconapin (4 mM) exhibits weak inhibitory activity against porcine pancreatic lipase, inhibiting only 5.7% of the enzyme activity[2].
Gluconapin (0.15-3.0 μL/mL; 18 h) dose-dependently inhibits the growth of Xanthomonas campestris pv. campestris race 4 strain HRI1279A in vitro[3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
体内実験
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Slc:ddY mice (6-week-old, male)[2]
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Dosage:40 μmol/kg (14.9 mg/kg); 80 μmol/kg (29.8 mg/kg)
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Administration:p.o.; single dose (immediately before corn oil loading)
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Result:Showed a non-statistically significant tendency to decrease plasma triglyceride levels at 4-8 hours after administration (40 μmol/kg).
Significantly suppressed the elevation of plasma triglyceride levels at 3-8 hours after administration, and reduced the 8-hour area under the plasma triglyceride concentration curve (AUC) to 61.5 ± 6.8% of the control value (p < 0.05 vs.control) (80 μmol/kg).
化学情報
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CAS 番号 19041-09-9
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分子量 373.40
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分子式 C11H19NO9S2
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SMILES
O=S(O/N=C(CCC=C)\S[C@@H]1O[C@@H]([C@H]([C@@H]([C@H]1O)O)O)CO)(O)=O
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別名
3-Butenyl glucosinolate
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Structure Classification
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Initial Source
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. Padilla G, et al. Variation of glucosinolates in vegetable crops of Brassica rapa. Phytochemistry. 2007;68(4):536-545. [Content Brief]
[3]. Velasco P, et al. In vivo and in vitro effects of secondary metabolites against Xanthomonas campestris pv. campestris. Molecules. 2013;18(9):11131-11143. Published 2013 Sep 11. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)