Hydroxydione
Hydroxydione has an effect of general anesthetic. Hydroxydione is a neuroactive steroid it can be used for anaesthesia related research.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 303-01-5
- 分子式: C21H32O3
- 分子量:332.48
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
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生物活性
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Cats with chloralose 60 to 80 mg/kg[2]
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Dosage:5-100 mg/kg
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Administration:Intravenous injection; 5-100 mg/kg once
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Result:Produce severe respiratory depression, but showed no effect on the tibialis in response to excitation of its motor nerve under the condition of chloralose. Produced the usual substantial sustained hypotension seen in chloralosed cats to response the nictitating membrane to preganglionic excitation with a dose of 10 mg/kg. Repressed the respiration in chloralosed cats after a rapid injection.
化学情報
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CAS 番号 303-01-5
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分子量 332.48
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分子式 C21H32O3
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SMILES
C[C@@]12[C@](CC[C@@H]2C(CO)=O)([H])[C@@]3([H])[C@@](CC1)([H])[C@@]4([C@](CC(CC4)=O)([H])CC3)C
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. RUMKE CL. The influence of drugs on the duration of hexobarbital and hydroxydione narcosis in mice. Naunyn Schmiedebergs Arch Exp Pathol Pharmakol. 1963;244:519-30. [Content Brief]
[2]. LERMAN LH, PATON WD. Experiments on the pharmacology of hydroxydione sodium succinate. Br J Pharmacol Chemother. 1960 Sep;15(3):458-65. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)