INK4C-IN-3
INK4C-IN-3 is a synthetic coumarin amide compound and a small-molecule inhibitor of INK4C (p18INK4C). INK4C-IN-3 promotes the ex vivo expansion of human and mouse hematopoietic stem cells. INK4C-IN-3 can be used in research related to hematopoietic stem cell expansion.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 1111287-26-3
- 分子式: C19H16N2O4
- 分子量:336.34
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
製品説明
体外実験
INK4C-IN-3 (0.01-1 μM; 7 days) promotes the ex vivo expansion of human umbilical cord blood CD34+ hematopoietic stem cells[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:human umbilical cord blood CD34+ hematopoietic stem cells
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Concentration:0.01, 0.1, 1 μM
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Incubation Time:7 days
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Result:Promoted the ex vivo expansion of human umbilical cord blood CD34+ hematopoietic stem cells.
化学情報
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CAS 番号 1111287-26-3
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分子量 336.34
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分子式 C19H16N2O4
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SMILES
O=C(C1=CC=C(C=C1)NC(C)=O)NC2=CC(OC3=O)=C(C(C)=C3)C=C2
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. Ronad PM, et al. Synthesis and evaluation of anti-inflammatory and analgesic activities of a novel series of substituted-N-(4-methyl-2-oxo-2H-chromen-7-yl) benzamides. Arzneimittelforschung. 2008;58(12):641-6. [Content Brief]
[2]. Xie XQ, et al. Discovery of novel INK4C small-molecule inhibitors to promote human and murine hematopoietic stem cell ex vivo expansion. Scientific reports. 2015 Dec 18;5:18115. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
INK4C-IN-3 関連分類
HY-123592 関連分類
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