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製品番号: HY-N12431

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Machilin A

Machilin A is a lignan isolated from the methanolic extract of Phoebe bark. Machilin A inhibits melanin biosynthesis in B-16 mouse melanoma cells with an IC₅₀ of 39.9 μM.

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CAS 番号: 110269-50-6
分子式: C₂₀H₂₂O₄
分子量:326.39

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (264 KB)

Machilin A 構造式

CAS 番号: 110269-50-6

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

Machilin A is a lignan isolated from the methanolic extract of Phoebe bark. Machilin A inhibits melanin biosynthesis in B-16 mouse melanoma cells with an IC₅₀ of 39.9 μM.

Cellular Effect

Cell Line	Type	Value	Description	References
A-375	IC₅₀	235.5 μM Compound: 2d	Cytotoxicity against human A375 cells after 5 days by MTT assay Cytotoxicity against human A375 cells after 5 days by MTT assay	[PMID: 19615898]
HepG2	IC₅₀	175.3 μM Compound: 2d	Cytotoxicity against human HepG2 cells after 5 days by MTT assay Cytotoxicity against human HepG2 cells after 5 days by MTT assay	[PMID: 19615898]
HT-29	IC₅₀	89.9 μM Compound: 2d	Cytotoxicity against human HT-29 cells after 5 days by MTT assay Cytotoxicity against human HT-29 cells after 5 days by MTT assay	[PMID: 19615898]
MCF7	IC₅₀	102.7 μM Compound: 2d	Cytotoxicity against human MCF7 cells after 5 days by MTT assay Cytotoxicity against human MCF7 cells after 5 days by MTT assay	[PMID: 19615898]

化学情報

CAS 番号 110269-50-6
分子量 326.39
分子式 C₂₀H₂₂O₄
SMILES

C[C@H](CC1=CC=C(OCO2)C2=C1)[C@@H](C)CC3=CC=C(OCO4)C4=C3
Structure Classification
- Phenylpropanoids
- Lignans
Initial Source
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

バッチを選択:

純度: 99.98%

Assay: 99.98%

ee.: 99.98%

データシート (264 KB)
COA (2659 KB)
元素分析報告書 (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
取扱説明書 (2659 KB)

参考文献

[1]. Li G, et al.Melanin biosynthesis inhibitors from the bark of Machilus thunbergii. Biol Pharm Bull. 2003 Jul;26(7):1039-41. [Content Brief]

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

濃度濃度

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分子量分子量

希釈計算機

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濃度 _(開始) 濃度 _(開始)

体積 _(開始) 体積 _(開始)

濃度 _(終了) 濃度 _(終了)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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