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NAE-IN-3

NAE-IN-3 (compound 1) is a potent, selective and non-covalent competitive NEDD8-activating enzyme (NAE) inhibitor (IC50 = 0.8 μM). NAE-IN-3 inhibits NAE by blocking the ATP-binding domain. NAE-IN-3 exhibits selectivity over analogous E1 enzymes UAE and SAE. NAE-IN-3 can be used for cancer research.

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  • CAS 番号: 951950-33-7
  • 分子式: C17H18N4O6
  • 分子量:374.35
  • 保管条件:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • NAE-IN-3 Chemical Structure
    NAE-IN-3 構造式
CAS 番号: 951950-33-7
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  • NAE-IN-3 Chemical Structure
    NAE-IN-3 Chemical Structure
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  • NAE-IN-3