Nagilactone C
Nagilactone C is a diterpene dilactone compound isolated from Podocarpus neriifolius. Nagilactone C has potent antiproliferative activity against human fibrosarcoma and murine colon carcinoma tumor cell lines.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 24338-53-2
- 分子式: C19H22O7
- 分子量:362.37
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| AGS | IC50 |
2.3 μM
Compound: 7j
|
Cytotoxicity against human AGS cells incubated for 48 hrs by MTT assay
Cytotoxicity against human AGS cells incubated for 48 hrs by MTT assay
|
[PMID: 33289552] |
| HeLa | IC50 |
3.3 μM
Compound: 7j
|
Cytotoxicity against human HeLa cells incubated for 48 hrs by MTT assay
Cytotoxicity against human HeLa cells incubated for 48 hrs by MTT assay
|
[PMID: 33289552] |
| HepG2 | IC50 |
14 μM
Compound: 7j
|
Cytotoxicity against human HepG2 cells incubated for 48 hrs by MTT assay
Cytotoxicity against human HepG2 cells incubated for 48 hrs by MTT assay
|
[PMID: 33289552] |
| MDA-MB-231 | IC50 |
5 μM
Compound: 7j
|
Cytotoxicity against human MDA-MB-231 cells incubated for 48 hrs by MTT assay
Cytotoxicity against human MDA-MB-231 cells incubated for 48 hrs by MTT assay
|
[PMID: 33289552] |
| P388 | IC50 |
0.33 μg/mL
Compound: 1
|
Cytotoxicity against mouse P388 cells
Cytotoxicity against mouse P388 cells
|
[PMID: 1800635] |
| PANC-1 | IC50 |
>40 μM
Compound: 7j
|
Cytotoxicity against human Panc-1 cells incubated for 48 hrs by MTT assay
Cytotoxicity against human Panc-1 cells incubated for 48 hrs by MTT assay
|
[PMID: 33289552] |
化学情報
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CAS 番号 24338-53-2
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分子量 362.37
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分子式 C19H22O7
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SMILES
C[C@@]1(C2=C3)[C@]4([H])[C@]([C@@H](O)[C@@H]5[C@H]1O5)(C(O[C@]4([H])[C@H](O)C2=C(C(C)C)OC3=O)=O)C
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Structure Classification
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Initial Source
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)