NDBM
NDBM is a probe and binds to tumor-specific Pim-1 kinase, releases strong fluorescence, and produces cytotoxicity, thus achieving cell screening and killing effects. NDBM can specifically target lysosomes and sensitively respond to pH. NDBM can be used to track the pH changes in the intracellular environment under conditions of autophagy and external stimulation.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 2958641-42-2
- 分子式: C33H35BrN4O7
- 分子量:679.56
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
Pim-1[1]
NDBM (2.5, 5, 10 and 20 μM, 18 h) decreases the survival rate of tumor cells (MGC-803, HepG2 and Hela) [1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 2958641-42-2
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分子量 679.56
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分子式 C33H35BrN4O7
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SMILES
BrC1=CC=C2OC(C(NCCOCCOCCN3C(C4=C5C(C(NCCN6CCOCC6)=CC=C5C3=O)=CC=C4)=O)=O)=CC2=C1
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)