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United States

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製品番号: HY-156275

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OSBP-IN-1

OSBP-IN-1(compound 12) is a Schweinfurthins analogues targeted of oxysterol-binding protein (OSBP). OSBP-IN-1 has antitumor activity.

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CAS 番号: 2890760-43-5
分子式: C₃₀H₃₆O₆
分子量:492.60

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

OSBP-IN-1 構造式

CAS 番号: 2890760-43-5

価格（税別）

Amount: USD 0.00

* アイテムを追加する前、数量をご選択ください

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性
- 製品説明
- IC₅₀ & Target
- Cellular Effect
化学情報
純度とドキュメンテーション
参考文献
Calculators
Help & FAQs
関連分類
Bioz

生物活性

製品説明

OSBP-IN-1(compound 12) is a Schweinfurthins analogues targeted of oxysterol-binding protein (OSBP). OSBP-IN-1 has antitumor activity^[1].

IC₅₀ & Target

12.4 n (MU-87 MG)^[1]

Cellular Effect

Cell Line	Type	Value	Description	References
A549	IC₅₀	733 nM Compound: 12	Antiproliferative activity against human A549 cells assessed as inhibition of cell proliferation incubated for 72 hrs by CellTiter-Glo luminescent assay Antiproliferative activity against human A549 cells assessed as inhibition of cell proliferation incubated for 72 hrs by CellTiter-Glo luminescent assay	[PMID: 37795600]
U-87MG ATCC	IC₅₀	12.4 nM Compound: 12	Antiproliferative activity against human U-87 MG cells assessed as inhibition of cell proliferation incubated for 72 hrs by CellTiter-Glo luminescent assay Antiproliferative activity against human U-87 MG cells assessed as inhibition of cell proliferation incubated for 72 hrs by CellTiter-Glo luminescent assay	[PMID: 37795600]

化学情報

CAS 番号 2890760-43-5
分子量 492.60
分子式 C₃₀H₃₆O₆
SMILES

C[C@@]12[C@](C(C)([C@@H](CC2)OC=O)C)([H])CC3=CC(/C=C/C4=CC(O)=C(CCC(C)(O5)C)C5=C4)=CC(O)=C3O1
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

バッチを選択:

純度: 99.98%

Assay: 99.98%

ee.: 99.98%

データシート (266 KB)
COA (2659 KB)
元素分析報告書 (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
取扱説明書 (2659 KB)

参考文献

[1]. Jézéquel G, et al. Structure-Based Design of a Lead Compound Derived from Natural Schweinfurthins with Antitumor Properties That Target Oxysterol-Binding Protein [published online ahead of print, 2023 Oct 5]. J Med Chem. 2023;10.1021/acs.jmedchem.3c01298. [Content Brief]

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

濃度濃度

体積体積

分子量分子量

希釈計算機

濃度 _(開始) × 体積 _(開始) = 濃度 _(終了) × 体積 _(終了)

濃度 _(開始) 濃度 _(開始)

体積 _(開始) 体積 _(開始)

濃度 _(終了) 濃度 _(終了)

体積 _(終了) 体積 _(終了)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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