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p53 Activator 14

p53 Activator 14 (Compound 7A) is a derivative of Neratinib (HY-32721), that induces DNA damage, activates p53, and inhibits the proliferation of multi cancer cells (IC50=7.21 μM for HCT116 cell). p53 Activator 14 inhibits the adhesion, migration and invasion of HCT116, arrests the cell cycle, and induces apoptosis. p53 Activator 14 inhibits angiogenesis and exhibits antitumor efficacy in chick chorioallantoic membrane (CAM) model.

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  • CAS 番号: 2922588-44-9
  • 分子式: C28H29ClN4O3
  • 分子量:505.01
  • 保管条件:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • p53 Activator 14 Chemical Structure
    p53 Activator 14 構造式
CAS 番号: 2922588-44-9
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