RU-39411
RU-39411 is a steroidal anti-estrogen with mixed estrogenic/antiestrogen activity. RU-39411 has shown inhibitory effects on cell growth in the MCF-7 breast cancer model, with the effect being correlated with its binding affinity to the estrogen receptor. RU-39411 was able to downregulate the estrogen binding capacity of cells, but did not reduce estrogen receptor mRNA levels, indicating that the grafting of its side chain prevents the antagonistic effects usually associated with steroidal estrogens. The administration of RU-39411 can promote the synthesis of progesterone receptors, further supporting its activity as an estrogen.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 120382-04-9
- 分子式: C28H37NO3
- 分子量:435.60
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- プロトコル
- 純度とドキュメンテーション
- 参考文献
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生物活性
製品説明
化学情報
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CAS 番号 120382-04-9
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分子量 435.60
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分子式 C28H37NO3
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SMILES
C[C@@]12[C@H](CC[C@]1([C@@]3(CCC4=C([C@]3([C@H](C2)C5=CC=C(C=C5)OCCN(C)C)[H])C=CC(O)=C4)[H])[H])O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
RU-39411 関連分類
HY-117649 関連分類
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