S3QEL-2
Based on 1 Customer Validation
S3QEL-2, a suppressor of superoxide production from mitochondrial complex III, potently and selectively suppresses site IIIQo superoxide production (IC50=1.7 μM). S3QEL-2 does not affect oxidative phosphorylation, and normal electron flux. S3QEL-2 inhibits HIF-1α accumulation.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.62%
- CAS 番号: 890888-12-7
- 分子式: C19H25N5
- 分子量:323.44
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
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High-Throughput Bioactive Compound Library
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生物活性
S3QELs-2 protects against ROS-induced, JNK-mediated cell stress in pancreatic β-cells and S3QEL-2 strongly mitigates the oxidative stress-induced apoptosis that limits the yield of functional β-cells from intact islets[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 890888-12-7
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性状 Solid
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分子量 323.44
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分子式 C19H25N5
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Color Off-white to yellow
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SMILES
CCCN(CCC)C1=C2C(N(C3=CC=C(C)C(C)=C3)N=C2)=NC=N1
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year
溶剤 & 溶解度
DMSO : 20.83 mg/mL (64.40 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (276 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.0918 mL | 15.4588 mL | 30.9176 mL | 77.2941 mL |
| 5 mM | 0.6184 mL | 3.0918 mL | 6.1835 mL | 15.4588 mL | |
| 10 mM | 0.3092 mL | 1.5459 mL | 3.0918 mL | 7.7294 mL | |
| 15 mM | 0.2061 mL | 1.0306 mL | 2.0612 mL | 5.1529 mL | |
| 20 mM | 0.1546 mL | 0.7729 mL | 1.5459 mL | 3.8647 mL | |
| 25 mM | 0.1237 mL | 0.6184 mL | 1.2367 mL | 3.0918 mL | |
| 30 mM | 0.1031 mL | 0.5153 mL | 1.0306 mL | 2.5765 mL | |
| 40 mM | 0.0773 mL | 0.3865 mL | 0.7729 mL | 1.9324 mL | |
| 50 mM | 0.0618 mL | 0.3092 mL | 0.6184 mL | 1.5459 mL | |
| 60 mM | 0.0515 mL | 0.2576 mL | 0.5153 mL | 1.2882 mL |
S3QEL-2 関連分類
HY-110282 関連分類
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