SMARt751
Based on 1 Customer Validation
SMARt751 targets the transcriptional regulatory factor VirS, inhibits its DNA binding ability, upregulates the mymA operon expression, thereby activating Ethionamide (HY-B0276), enhancing the antimicrobial activity of Ethionamide. SMARt751 enhances the antibacterial activity of Ethionamide against M. tuberculosis, reverses the Ethionamide resistance. SMARt751 improves the antibacterial effect of Ethionamide and reduces its effective dose in mouse models.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.99%
- CAS 番号: 1616370-52-5
- 分子式: C15H17F4NO
- 分子量:303.30
-
保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
生物活性
化学情報
-
CAS 番号 1616370-52-5
-
性状 Solid
-
分子量 303.30
-
分子式 C15H17F4NO
-
Color White to off-white
-
SMILES
O=C(CCC(F)(F)F)N1CCC(CC1)C2=CC=C(C=C2)F
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
DMSO : 100 mg/mL (329.71 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
-
データシート (268 KB)
-
SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
-
取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.2971 mL | 16.4853 mL | 32.9707 mL | 82.4266 mL |
| 5 mM | 0.6594 mL | 3.2971 mL | 6.5941 mL | 16.4853 mL | |
| 10 mM | 0.3297 mL | 1.6485 mL | 3.2971 mL | 8.2427 mL | |
| 15 mM | 0.2198 mL | 1.0990 mL | 2.1980 mL | 5.4951 mL | |
| 20 mM | 0.1649 mL | 0.8243 mL | 1.6485 mL | 4.1213 mL | |
| 25 mM | 0.1319 mL | 0.6594 mL | 1.3188 mL | 3.2971 mL | |
| 30 mM | 0.1099 mL | 0.5495 mL | 1.0990 mL | 2.7476 mL | |
| 40 mM | 0.0824 mL | 0.4121 mL | 0.8243 mL | 2.0607 mL | |
| 50 mM | 0.0659 mL | 0.3297 mL | 0.6594 mL | 1.6485 mL | |
| 60 mM | 0.0550 mL | 0.2748 mL | 0.5495 mL | 1.3738 mL | |
| 80 mM | 0.0412 mL | 0.2061 mL | 0.4121 mL | 1.0303 mL | |
| 100 mM | 0.0330 mL | 0.1649 mL | 0.3297 mL | 0.8243 mL |