TNIK-IN-4
TNIK-IN-4 is a potent TNIK inhibitor with IC50 of 0.61 μM. TNIK-IN-4 has inhibitory activity against typical colorectal cancer cell line HCT116.
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- CAS 番号: 2754266-04-9
- 分子式: C20H16FN3O3
- 分子量:365.36
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
IC50: 0.61 μM (TNIK)[1]
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HCT-116 | IC50 |
36.423 μM
Compound: 5a
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Antiproliferative activity against human HCT-116 cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay
Antiproliferative activity against human HCT-116 cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay
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[PMID: 35447345] |
TNIK-IN-4 (compound 5a) (0.4-100 μM; 72 hours) has inhibitory activity against typical colorectal cancer cell line HCT116 with IC50 of 36.423 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:HCT116 cells[1]
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Concentration:0.4, 1.2, 3.7, 11.1, 33.3 and 100 μM
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Incubation Time:72 hours
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Result:Showed inhibitory activity against typical colorectal cancer cell line HCT116 with IC50 of 36.423 μM.
化学情報
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CAS 番号 2754266-04-9
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分子量 365.36
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分子式 C20H16FN3O3
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SMILES
O=C1OC2=CC(C3=CC(OC)=C(N)N=C3)=CC=C2N1CC4=CC=C(F)C=C4
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
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