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Cat. No.: HY-157658

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K-8794

K-8794 is an orally active selective endothelin receptor ET_B antagonist that can be used in research on cardiovascular diseases.

For research use only. We do not sell to patients.

CAS No.: 180577-26-8
Formula: C₃₆H₃₈N₆O₆S
Molecular Weight:682.79

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

K-8794 Chemical Structure

CAS No.: 180577-26-8

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

K-8794 is an orally active selective endothelin receptor ET_B antagonist that can be used in research on cardiovascular diseases^[1].

All Endothelin Receptor Isoforms :

ET_A
ET_B

Chemical Information

CAS No. 180577-26-8
Molecular Weight 682.79
Formula C₃₆H₃₈N₆O₆S
SMILES

O=C(CCOC1=NC(C2=NC=CC=N2)=NC(NS(=O)(C3=CC=C(C(C)(C)C)C=C3)=O)=C1OC4=C(OC)C=CC=C4)NC5=C(C)C=CC=C5C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Yuyama H, et al. Pharmacological characterization of YM598, an orally active and highly potent selective endothelin ETA receptor antagonist[J]. European journal of pharmacology, 2003, 478(1): 61-71. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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