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Cat. No.: HY-19238

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BMS-181885

BMS-181885 is a selective 5-HT₁ receptor agonist and a ligand for 5-HT_1B/_1D receptors. BMS-181885 exhibits anti-migraine activity. BMS-181885 can be used in the research of neurological diseases such as migraine.

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CAS No.: 165250-47-5
화학식: C₂₅H₂₈N₆O₃
분자량:460.53

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

BMS-181885 Chemical Structure

CAS No.: 165250-47-5

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

IC₅₀ & Target^[1]

5-HT₁ Receptor

All 5-HT Receptor Isoforms :

Chemical Information

CAS No. 165250-47-5
분자량 460.53
화학식 C₂₅H₂₈N₆O₃
SMILES

O=C1C(C(NC2=CC3=C(NC=C3CCCN4CCN(C5=NC=NC=C5OC)CC4)C=C2)=C1C)=O
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Srinivas NR, et al. Absolute bioavailability and dose proportionality of BMS-181885, an antimigraine agent, following the administration of single intranasal doses to cynomolgus monkeys. J Pharm Sci. 1998 Sep;87(9):1170-2. [Content Brief]

[2]. Schulze G E, et al. Intranasal toxicity of BMS-181885, a novel 5-HT1 agonist. International journal of toxicology, 1999, 18(5): 285-296.

[3]. Saxena PR, et al. BMS-181885, a 5-HT1B/1D receptor ligand, in experimental models predictive of antimigraine activity and coronary side-effect potential. Eur J Pharmacol. 1998 Jun 26;351(3):329-39. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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Biological Activity
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- IC₅₀ & Target
Chemical Information
순도&문서
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BMS-181885

All 5-HT Receptor Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

BMS-181885 Related Classifications

HY-19238 Related Classifications