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Cat. No.: HY-146686

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BuChE-IN-3

BuChE-IN-3 (Compound C4) is a potent inhibitor of BuChE with an IC₅₀ of 8.3 nM. BuChE-IN-3 exhibits mild antioxidant capacity, nontoxicity, lipophilicity and neuroprotective activity.

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CAS No.: 2499488-78-5
화학식: C₂₁H₂₁F₂N₃O₄S
분자량:449.47

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (272 KB)

BuChE-IN-3 Chemical Structure

CAS No.: 2499488-78-5

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

제품 설명

BuChE-IN-3 (Compound C4) is a potent inhibitor of BuChE with an IC₅₀ of 8.3 nM. BuChE-IN-3 exhibits mild antioxidant capacity, nontoxicity, lipophilicity and neuroprotective activity^[1].

All Cholinesterase (ChE) Isoforms :

AChE
BChE

Chemical Information

CAS No. 2499488-78-5
분자량 449.47
화학식 C₂₁H₂₁F₂N₃O₄S
SMILES

O=S1(CCC2=C(N(N=C2CN(CC3=CC=C(C=C3)F)CCO)C4=CC=CC=C4F)O1)=O
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (272 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Zhang Z, et al. The structure-based optimization of δ-sultone-fused pyrazoles as selective BuChE inhibitors. Eur J Med Chem. 2020 Sep 1;201:112273. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

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Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

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100 mg

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Biological Activity
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Chemical Information
순도&문서
References

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BuChE-IN-3

All Cholinesterase (ChE) Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

BuChE-IN-3 Related Classifications

HY-146686 Related Classifications