Defoslimod
Defoslimod (OM 174) is an agonist for TLR4 receptor and acts as an immunomodulator. Defoslimod activates macrophages and dendritic cells, induces cytokines secretion, and exhibits antitumor efficacy in rats.
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- CAS No.: 171092-39-0
- 화학식: C52H100N2O20P2
- 분자량:1135.30
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Macrophage | EC50 |
0.025 μg/mL
Compound: OM-174
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Induction of NO production in murine macrophage
Induction of NO production in murine macrophage
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[PMID: 17004714] |
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 171092-39-0
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분자량 1135.30
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화학식 C52H100N2O20P2
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SMILES
O=P(O)(O)O[C@H]([C@@H]([C@H]([C@@H]1O)O)NC(C[C@H](O)CCCCCCCCCCC)=O)O[C@@H]1CO[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)OP(O)(O)=O)O)NC(C[C@@H](CCCCCCCCCCC)OC(CCCCCCCCCCC)=O)=O
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Synonyms
OM 174
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Defoslimod Related Classifications
HY-164386 Related Classifications
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