Dicloromezotiaz
Based on 1 Customer Validation
Dicloromezotiaz is a potent insecticide acting on nicotinic acetylcholine receptors (nAChRs). Dicloromezotiaz can be used to control a broad range of lepidoptera.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- Purity : 99.07%
- CAS No.: 1263629-39-5
- 화학식: C19H12Cl3N3O2S
- 분자량:452.74
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보관:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
제품 설명
In Vitro
Chemical Information
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CAS No. 1263629-39-5
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Appearance Solid
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분자량 452.74
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화학식 C19H12Cl3N3O2S
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Color Light yellow to green yellow
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SMILES
O=C1[C-](C2=CC(Cl)=CC(Cl)=C2)C([N+](CC3=CN=C(Cl)S3)=C4C(C)=CC=CN14)=O
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
용액&용해도
In Vitro:
DMSO : 100 mg/mL (220.88 mM; ultrasonic and warming and heat to 80°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
In Vivo:
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
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%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
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%+
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+%Tween-80 + +
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%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL.
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
순도&문서
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Data Sheet (278 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.2088 mL | 11.0439 mL | 22.0877 mL | 55.2193 mL |
| 5 mM | 0.4418 mL | 2.2088 mL | 4.4175 mL | 11.0439 mL | |
| 10 mM | 0.2209 mL | 1.1044 mL | 2.2088 mL | 5.5219 mL | |
| 15 mM | 0.1473 mL | 0.7363 mL | 1.4725 mL | 3.6813 mL | |
| 20 mM | 0.1104 mL | 0.5522 mL | 1.1044 mL | 2.7610 mL | |
| 25 mM | 0.0884 mL | 0.4418 mL | 0.8835 mL | 2.2088 mL | |
| 30 mM | 0.0736 mL | 0.3681 mL | 0.7363 mL | 1.8406 mL | |
| 40 mM | 0.0552 mL | 0.2761 mL | 0.5522 mL | 1.3805 mL | |
| 50 mM | 0.0442 mL | 0.2209 mL | 0.4418 mL | 1.1044 mL | |
| 60 mM | 0.0368 mL | 0.1841 mL | 0.3681 mL | 0.9203 mL | |
| 80 mM | 0.0276 mL | 0.1380 mL | 0.2761 mL | 0.6902 mL | |
| 100 mM | 0.0221 mL | 0.1104 mL | 0.2209 mL | 0.5522 mL |