EU101
EU101 (NOV1801) is a humanized agonistic monoclonal antibody targeting the costimulatory receptor CD137, with potential immunostimulatory and antineoplastic activities.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
제품 설명
Species Reactivity
Human
In Vitro
EU101 can target and bind to CD137 expressed on various leukocyte subsets, enhance CD137-mediated signaling, induce the proliferation of cytotoxic T lymphocytes and cytokine production, and promote cytotoxic T lymphocyte-mediated anti-tumor immune responses. Meanwhile, it can also induce natural killer cell-mediated tumor cell killing and suppress the immunosuppressive activity of regulatory T cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Gene ID
Accession
Target
TNFRSF9/4-1BB/CD137
Conjugated
Unconjugated
Reconsititution
The product can be reconstituted/diluted with sterile PBS or saline.
신청
ELISA, FACS, Functional assay
Chemical Information
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SMILES
[EU101]
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Synonyms
NOV1801
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Formulation
Please refer to the lot-specific COA for specific buffer information.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
[1]. EU101.
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)