Fluorescein-DBCO
Based on 1 Customer Validation
Fluorescein-DBCO is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fluorescein-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- Purity: 98.02%
- CAS No.: 2054339-00-1
- 화학식: C39H27N3O6S
- 분자량:665.71
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보관:
4°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
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Biological Activity
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Chemical Information
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용액&용해도
- 순도&문서
- References
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Help & FAQs
Biological Activity
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Non-cleavable Linker |
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2054339-00-1
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Appearance Solid
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분자량 665.71
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화학식 C39H27N3O6S
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Color Yellow to orange
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SMILES
O=C(N1CC2=C(C#CC3=C1C=CC=C3)C=CC=C2)CCNC(NC4=CC=C(C5=C4)C6(OC5=O)C7=C(OC8=C6C=CC(O)=C8)C=C(O)C=C7)=S
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선적
Room temperature in continental US; may vary elsewhere.
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보관
4°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
용액&용해도
DMSO : 100 mg/mL (150.22 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
순도&문서
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Data Sheet (273 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| DMSO | 1 mM | 1.5022 mL | 7.5108 mL | 15.0216 mL | 37.5539 mL |
| 5 mM | 0.3004 mL | 1.5022 mL | 3.0043 mL | 7.5108 mL | |
| 10 mM | 0.1502 mL | 0.7511 mL | 1.5022 mL | 3.7554 mL | |
| 15 mM | 0.1001 mL | 0.5007 mL | 1.0014 mL | 2.5036 mL | |
| 20 mM | 0.0751 mL | 0.3755 mL | 0.7511 mL | 1.8777 mL | |
| 25 mM | 0.0601 mL | 0.3004 mL | 0.6009 mL | 1.5022 mL | |
| 30 mM | 0.0501 mL | 0.2504 mL | 0.5007 mL | 1.2518 mL | |
| 40 mM | 0.0376 mL | 0.1878 mL | 0.3755 mL | 0.9388 mL | |
| 50 mM | 0.0300 mL | 0.1502 mL | 0.3004 mL | 0.7511 mL | |
| 60 mM | 0.0250 mL | 0.1252 mL | 0.2504 mL | 0.6259 mL | |
| 80 mM | 0.0188 mL | 0.0939 mL | 0.1878 mL | 0.4694 mL | |
| 100 mM | 0.0150 mL | 0.0751 mL | 0.1502 mL | 0.3755 mL |
Fluorescein-DBCO Related Classifications
HY-126851 Related Classifications
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