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Cat. No.: HY-172944

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GPR40 Activator 3

GPR40 Activator 3 (compound SC) is a potent GPR40 activator. GPR40 Activator 3 mitigates pulmonary fibrosis by inhibiting M2 macrophage polarization via the GPR40/PKD1/CD36 axis.

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CAS No.: 2980-31-6
화학식: C₁₄H₁₀O₅
분자량:258.23

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

GPR40 Activator 3 Chemical Structure

CAS No.: 2980-31-6

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- Cellular Effect
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

GPR40 Activator 3 (compound SC) is a potent GPR40 activator. GPR40 Activator 3 mitigates pulmonary fibrosis by inhibiting M2 macrophage polarization via the GPR40/PKD1/CD36 axis^[1].

All Free Fatty Acid Receptor Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
HepG2	IC₅₀	32.52 μM Compound: 2g	Growth inhibition of human HepG2 cells after 24 hrs by MTT assay Growth inhibition of human HepG2 cells after 24 hrs by MTT assay	[PMID: 29609121]
MCF7	IC₅₀	>200 μM Compound: 2g	Growth inhibition of human MCF7 cells after 24 hrs by MTT assay Growth inhibition of human MCF7 cells after 24 hrs by MTT assay	[PMID: 29609121]
MDA-MB-231	IC₅₀	65.98 μM Compound: 2g	Growth inhibition of human MDA-MB-231 cells after 24 hrs by MTT assay Growth inhibition of human MDA-MB-231 cells after 24 hrs by MTT assay	[PMID: 29609121]

Chemical Information

CAS No. 2980-31-6
분자량 258.23
화학식 C₁₄H₁₀O₅
SMILES

O=C1C2=C(OC3=C1C(OC)=CC=C3)C=C(O)C=C2O
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Wan HQ, et al. GPR40 activation alleviates pulmonary fibrosis by repressing M2 macrophage polarization through the PKD1/CD36/TGF-β1 pathway. Acta Pharmacol Sin. 2025 May 14. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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Biological Activity
- 제품 설명
Chemical Information
순도&문서
References

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GPR40 Activator 3

All Free Fatty Acid Receptor Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

GPR40 Activator 3 Related Classifications

HY-172944 Related Classifications