Grifolic acid
Grifolic acid is a phenolic compound that is first extracted from the mushroom Albatrellus confluens. Grifolic acid acts as an agonist of the free fatty acid receptor (FFAR4/GPR120).
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- Purity: 98.0%
- CAS No.: 80557-12-6
- 화학식: C23H32O4
- 분자량:372.50
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보관:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
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Biological Activity
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Chemical Information
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용액&용해도
- 순도&문서
- References
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Help & FAQs
Biological Activity
제품 설명
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| DU-145 | IC50 |
5.7 μM
Compound: 7
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Antiproliferative activity against LPA-induced human DU-145 cells
Antiproliferative activity against LPA-induced human DU-145 cells
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[PMID: 33843223] |
In Vitro
Grifolic acid (2.5-20 μM) treatment reduces RAW264.7 cell viability in a dose and time dependent manner[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 80557-12-6
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Appearance Solid
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분자량 372.50
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화학식 C23H32O4
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Color White to off-white
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SMILES
O=C(O)C1=C(C)C=C(O)C(C/C=C(C)/CC/C=C(C)/CC/C=C(C)\C)=C1O
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Structure Classification
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Initial Source
fungus Albatrellus confluens
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선적
Room temperature in continental US; may vary elsewhere.
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보관
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
용액&용해도
In Vitro:
DMSO : 100 mg/mL (268.46 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
순도&문서
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Data Sheet (267 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.6846 mL | 13.4228 mL | 26.8456 mL | 67.1141 mL |
| 5 mM | 0.5369 mL | 2.6846 mL | 5.3691 mL | 13.4228 mL | |
| 10 mM | 0.2685 mL | 1.3423 mL | 2.6846 mL | 6.7114 mL | |
| 15 mM | 0.1790 mL | 0.8949 mL | 1.7897 mL | 4.4743 mL | |
| 20 mM | 0.1342 mL | 0.6711 mL | 1.3423 mL | 3.3557 mL | |
| 25 mM | 0.1074 mL | 0.5369 mL | 1.0738 mL | 2.6846 mL | |
| 30 mM | 0.0895 mL | 0.4474 mL | 0.8949 mL | 2.2371 mL | |
| 40 mM | 0.0671 mL | 0.3356 mL | 0.6711 mL | 1.6779 mL | |
| 50 mM | 0.0537 mL | 0.2685 mL | 0.5369 mL | 1.3423 mL | |
| 60 mM | 0.0447 mL | 0.2237 mL | 0.4474 mL | 1.1186 mL | |
| 80 mM | 0.0336 mL | 0.1678 mL | 0.3356 mL | 0.8389 mL | |
| 100 mM | 0.0268 mL | 0.1342 mL | 0.2685 mL | 0.6711 mL |
Grifolic acid Related Classifications
HY-N3977 Related Classifications
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