Hydroxydione
Hydroxydione has an effect of general anesthetic. Hydroxydione is a neuroactive steroid it can be used for anaesthesia related research.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- CAS No.: 303-01-5
- 화학식: C21H32O3
- 분자량:332.48
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Biological Activity
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Cats with chloralose 60 to 80 mg/kg[2]
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Dosage:5-100 mg/kg
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Administration:Intravenous injection; 5-100 mg/kg once
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Result:Produce severe respiratory depression, but showed no effect on the tibialis in response to excitation of its motor nerve under the condition of chloralose. Produced the usual substantial sustained hypotension seen in chloralosed cats to response the nictitating membrane to preganglionic excitation with a dose of 10 mg/kg. Repressed the respiration in chloralosed cats after a rapid injection.
Chemical Information
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CAS No. 303-01-5
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분자량 332.48
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화학식 C21H32O3
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SMILES
C[C@@]12[C@](CC[C@@H]2C(CO)=O)([H])[C@@]3([H])[C@@](CC1)([H])[C@@]4([C@](CC(CC4)=O)([H])CC3)C
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
[1]. RUMKE CL. The influence of drugs on the duration of hexobarbital and hydroxydione narcosis in mice. Naunyn Schmiedebergs Arch Exp Pathol Pharmakol. 1963;244:519-30. [Content Brief]
[2]. LERMAN LH, PATON WD. Experiments on the pharmacology of hydroxydione sodium succinate. Br J Pharmacol Chemother. 1960 Sep;15(3):458-65. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Hydroxydione Related Classifications
HY-148156 Related Classifications
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