MDTF
Based on 1 Customer Validation
MDTF is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- Purity: 95.64%
- 화학식: C16H10F4NNaO9S
- 분자량:491.30
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보관:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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용액&용해도
- 순도&문서
- References
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Help & FAQs
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Biological Activity
MDTF (50 μM) increases hydrophilic character by substitution of a cyclohexyl ring and a MD-based FRET probe incubates in human plasma has a considerably higher self-stabilization rate compared to the MCC-based probe[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Appearance Solid
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분자량 491.30
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화학식 C16H10F4NNaO9S
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Color White to off-white
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SMILES
O=C([C@H]1CO[C@H](OC1)CN2C(C=CC2=O)=O)OC3=C(C(F)=C(C(F)=C3F)S(=O)(O[Na])=O)F
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
용액&용해도
DMSO : 100 mg/mL (203.54 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
순도&문서
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Data Sheet (272 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.0354 mL | 10.1771 mL | 20.3542 mL | 50.8854 mL |
| 5 mM | 0.4071 mL | 2.0354 mL | 4.0708 mL | 10.1771 mL | |
| 10 mM | 0.2035 mL | 1.0177 mL | 2.0354 mL | 5.0885 mL | |
| 15 mM | 0.1357 mL | 0.6785 mL | 1.3569 mL | 3.3924 mL | |
| 20 mM | 0.1018 mL | 0.5089 mL | 1.0177 mL | 2.5443 mL | |
| 25 mM | 0.0814 mL | 0.4071 mL | 0.8142 mL | 2.0354 mL | |
| 30 mM | 0.0678 mL | 0.3392 mL | 0.6785 mL | 1.6962 mL | |
| 40 mM | 0.0509 mL | 0.2544 mL | 0.5089 mL | 1.2721 mL | |
| 50 mM | 0.0407 mL | 0.2035 mL | 0.4071 mL | 1.0177 mL | |
| 60 mM | 0.0339 mL | 0.1696 mL | 0.3392 mL | 0.8481 mL | |
| 80 mM | 0.0254 mL | 0.1272 mL | 0.2544 mL | 0.6361 mL | |
| 100 mM | 0.0204 mL | 0.1018 mL | 0.2035 mL | 0.5089 mL |
MDTF Related Classifications
HY-150043A Related Classifications
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