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Cat. No.: HY-187523

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Methylolanthanin

Name: Methylolanthanin
Brand: MedChemExpress
SKU: HY-187523
Availability: PreOrder

(Synonyms: para-MLL)

Methylolanthanin (para-MLL) is a natural small-molecule metallophore identified in the culture supernatant of Methylobacterium extorquens AM1. Methylolanthanin binds lanthanide metal ions such as La³⁺, Nd³⁺ and Lu³⁺. It is applicable to studies related to lanthanide metabolism, bacterial metallophores, metal homeostasis and methylotrophic metabolism.

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CAS No.: 3120945-90-3
화학식: C₄₀H₅₈N₆O₁₁
분자량:798.92

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Methylolanthanin Chemical Structure

CAS No.: 3120945-90-3

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- In Vitro
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

All Endogenous Metabolite Isoforms :

In Vitro

Methylolanthanin (para-MLL) (10 μM; 15 min) forms insoluble complexes with La³⁺, Nd³⁺, Eu³⁺, and Lu³⁺ at pH 6.0, causing the complexes to precipitate from the solution^[1].
Methylolanthanin (18.75 μM) exhibits low iron (III)-binding affinity and only weak ability to compete with the CAS/HDTMA complex for Fe³⁺ at pH 6.0^[1].
Methylolanthanin forms the [MLL-H+Ln³⁺]²⁺ complex with La³⁺, Nd³⁺ and Lu³⁺^[2].
Methylolanthanin (50 nM) significantly increases the growth yield of M. extorquens AM1 ΔmxaF and ΔmxaFΔmll mutants under conditions of 2 μM or 50 nM NdCl₃^[2].
Methylolanthanin binds Eu³⁺ within the micromolar and nanomolar concentration ranges and forms detectable Eu³⁺-MLL particles, with a log K_SP of -12.07 for the precipitated complex^[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 3120945-90-3
분자량 798.92
화학식 C₄₀H₅₈N₆O₁₁
SMILES

O=C(C(CC(NCCCCN(CCCCNC(C1=CC=C(C=C1)O)=O)C(C)=O)=O)(CC(NCCCCN(CCCCNC(C2=CC=C(C=C2)O)=O)C(C)=O)=O)O)O
Synonyms

para-MLL
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Handling Instructions (2659 KB)

References

[1]. Mertens MW, et al. Synthesis of two methylolanthanin derivatives and the investigation of their lanthanide and iron binding capabilities. Dalton transactions (Cambridge, England : 2003). 2026 Jul 14. [Content Brief]

[2]. Zytnick AM, et al. Identification and characterization of a small-molecule metallophore involved in lanthanide metabolism. Proc Natl Acad Sci U S A. 2024;121(32):e2322096121.

[3]. Gutenthaler-Tietze SM, et al. Comparative Binding Studies of the Chelators Methylolanthanin and Rhodopetrobactin B to Lanthanides and Ferric Iron. ChemBioChem. 2026;27(1):e202500312.

Calculators

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

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MOQ

Minimum order quantity

100 mg

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