MTC420
MTC420 (compound 42a) is a heterocyclic quinolone compound that targets the respiratory chain of Mycobacterium tuberculosis and exhibits antituberculosis activity (Rep Mtb: IC50=525 nM, Wayne Mtb: IC50=76 nM, MDR Mtb: IC50=140 nM).
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- CAS No.: 2088930-66-7
- 화학식: C20H16F4N2O
- 분자량:376.35
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Protocol
- 순도&문서
- References
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Help & FAQs
Biological Activity
제품 설명
IC50 & Target
[1]|
Rep Mtb 525 nM (IC50) |
Wayne Mtb 76 nM (IC50) |
MDR Mtb 140 nM (IC50) |
Chemical Information
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CAS No. 2088930-66-7
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분자량 376.35
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화학식 C20H16F4N2O
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SMILES
FC1=C2C(NC(C3=CC=C(N4CCC(C4)(F)F)C=C3)=C(C)C2=O)=CC(F)=C1
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocol
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
MTC420 Related Classifications
HY-116943 Related Classifications
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